Comparative transcriptome analysis reveals metabolic regulation of prodigiosin in Serratia marcescens
نویسندگان
چکیده
منابع مشابه
Review of Prodigiosin, Pigmentation in Serratia marcescens
Prodigiosins, a family of natural red pigments characterized by a common pyrrolylpyrromethane skeleton, are produced by various bacteria that first characterized from Serratia marcescens. This pigment is a promising drug owing to its reported characteristics of having antifungal, immunosuppressive and anti-proliferative activity. From an industrial point of view to obtain optimal conditions to ...
متن کاملDefects in prodigiosin formation by L-forms of Serratia marcescens.
An L-form of Serratia marcescens has previously been shown incapable of producing the red pigment, prodigiosin, characteristic of the parent bacteria. Mutants of S. marcesens, unable to form one or the other of the two prodigiosin precursors, 4-methoxy-2,2'-bipyrrole-5-carboxaldehyde or 2-methyl-3-n-amylpyrrole, were used to test the nature of the L-form defect. The L-forms failed to form suffi...
متن کاملBiosynthesis of prodigiosin, a secondary metabolite of Serratia marcescens.
Prodigiosenes (prodigiosin and prodigiosin-like pigments) are known to be synthesized by only one genus of Eubacteriales and by two genera of Actinomycetales. Biosynthesis by Serratia marcescens occurs over a relatively narrow range of temperatures, although the bacteria grow over a broad range. When cultures of S. marcescens were incubated at 27 C in 1.0% casein hydrolysate, viable count and p...
متن کاملSpray-dried Prodigiosin from Serratia marcescens As A colorant
Encapsulation technique via spray drying can be employed to enhance the natural pigment’s properties. In this study, spray-dried microparticles containing red pigment (prodigiosin) extracted from Serratia marcescens was produced using κcarrageenan and maltodextrin as encapsulation agents. The effect of spray-drying parameters on the encapsulation yield (EY), particle size and color intensity of...
متن کاملRegulation of carbamylphosphate synthesis in Serratia marcescens.
Serratia marcescens HY possessed a single carbamylphosphate synthase (CPSase) which was subject to cumulative repression by arginine and a pyrimidine. CPSase did not appear to be a part of a multifunctional enzyme complex as is the case for other enzymes of pyrimidine biosynthesis in this organism. CPSase was purified to homogeneity. The molecular weight of the enzyme was estimated to be 167,00...
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ژورنال
عنوان ژورنال: Systems Microbiology and Biomanufacturing
سال: 2021
ISSN: 2662-7655,2662-7663
DOI: 10.1007/s43393-021-00028-w